منابع مشابه
SEPP 1 ( selenoprotein P , plasma , 1 )
Note SEPP1 belongs to selenoproteins, all of which contain selenium in the form of selenocysteine (SeC) and are being synthesized in the presence of UGA codon, specific stem loop structure in 3' UTR of mRNA called SECIS (Selenocysteine Insertion Sequence) and other specific factors. Selenoprotein P is a glycoprotein present mainly in plasma, where it accounts for 40 65% of total selenium in thi...
متن کاملSelenoprotein P in human plasma as an extracellular phospholipid hydroperoxide glutathione peroxidase. Isolation and enzymatic characterization of human selenoprotein p.
Selenoprotein P is an extracellular protein containing presumably 10 selenocysteines that are encoded by the UGA stop codon in the open reading frame of the mRNA. The function of selenoprotein P is currently unknown, although several indirect lines of evidence suggest that selenoprotein P is a free radical scavenger. We first developed a conventional procedure to isolate selenoprotein P from hu...
متن کاملA prospective study of plasma Selenoprotein P and lung cancer risk among low-income adults.
BACKGROUND Epidemiologic studies have shown increased risks of lung cancer among adults with low blood levels of selenium, although evidence is inconsistent. In the United States, the incidence of lung cancer is higher and mean serum selenium levels lower among Blacks than Whites, but prior studies have not assessed the selenium-lung cancer association among Blacks. METHODS From the prospecti...
متن کاملConserved features of selenoprotein P cDNA.
26. Berry, M. J., Banu, L., Harney, J. W. and Larsen, P. R. (1993) EMBO J. 12,3315-3322 Said, €3. Cole, J. K. and Nornura, M. (1988) Nucleic Acids Res. 16, 10529-10545 Cerretti, 1). P., Mattheakis, I,. C., Kearney, K. K., Vu, 1,. and Nomura, M. (1988) J. Mol. Biol. 204, 309-325 Rould, M. A,, Perona, J. J. and Steitz, T. A. (1991) Nature (London) 352,2 13-2 18 Bettany, A. J. E., Eisenstein, R. S...
متن کاملDomain structure of bi-functional selenoprotein P.
Human selenoprotein P (SeP), a selenium-rich plasma glycoprotein, is presumed to contain ten selenocysteine residues; one of which is located at the 40th residue in the N-terminal region and the remaining nine localized in the C-terminal third part. We have shown that SeP not only catalyses the reduction of phosphatidylcholine hydroperoxide by glutathione [Saito, Hayashi, Tanaka, Watanabe, Suzu...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2012
ISSN: 1768-3262
DOI: 10.4267/2042/46037